Bioactive Small Molecules

EP2175

EP2175 (click to show)

EP2175 (click to hide)

Title:

Selective activation of apoptosis by a novel set of 4-aryl-3-(3-aryl-1-oxo-2-propenyl)-2(1H)-quinolinones through a Myc-dependent pathway

Reference:

Cancer Letters, 2009 Feb 18;274(2):243-9.

Authors:

Gisela Claassen, Elena Brin, Candace Crogan-Grundy, Mei Ting Vaillancourt, Han Zhong Zhang, Sui Xiong Cai, John Drewe, Ben Tseng, Shailaja Kasibhatla

Compounds:

EP2175 (5509444), EP58269 {synthesized by authors; not in our database}