Bioactive Small Molecules

2-[5-(5-bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]succinic acid

Compound 79-6

Compound 79-6 (click to show)
Compound 79-6 (click to hide)
Title:
A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo
Reference:
Cancer Cell. 2010 Apr 13;17(4):400-11.
Authors:
Cerchietti LC, Ghetu AF, Zhu X, Da Silva GF, Zhong S, Matthews M, Bunting KL, Polo JM, Farès C, Arrowsmith CH, Yang SN, Garcia M, Coop A, Mackerell AD Jr, Privé GG, Melnick A.
Compounds:
Compound 79-6 (5364749), Compound 79-40 (6044763)