Bioactive Small Molecules

Compound 7, Compound 9

Compound 7 (click to show)

Compound 7 (click to hide)

Title:

Sirtuins inhibitors: The approach to affinity and selectivity

Reference:

Biochim Biophys Acta. 2010 Aug;1804(8):1635-44. Epub 2009 Nov 18.

Authors:

Yana Cen

Compounds:

Compound 7 (5327543)

Compound 9 (click to show)

Compound 9 (click to hide)

Title:

Thiobarbiturates as Sirtuin Inhibitors: Virtual Screening, Free-Energy Calculations, and Biological Testing

Reference:

ChemMedChem. 2008 Dec;3(12):1965-76.

Authors:

Urszula Uciechowska, Jorg Schemies, Robert C. Neugebauer, Elisabeth-Maria Huda

Compounds:

Compound 7 (6958028), Compound 8 (6988938), Compound 9 (5327543), Compound 10 (5549466), Compound 11 (5240507)