Bioactive Small Molecules

3PO

3PO (click to show)

3PO (click to hide)

Title:

Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth

Reference:

Molecular Cancer Therapeutics, 2008 Jan; 7(1):110-20

Authors:

Clem B, Telang S, Clem A, Yalcin A, Meier J, Simmons A, Rasku MA, Arumugam S, Dean WL, Eaton J, Lane A, Trent JO, Chesney J.

Compounds:

3PO (5284086)

3PO (click to show)

3PO (click to hide)

Title:

Block Copolymer Micelles for Controlled Delivery of Glycolytic Enzyme Inhibitors

Reference:

Pharmaceutical Research 2012 Mar;29(3):847-55

Authors:

Akter S, Clem BF, Lee HJ, Chesney J, Bae Y.

Compounds:

3PO (5284086)

3PO (click to show)

3PO (click to hide)

Title:

Targeting 6-phosphofructo-2-kinase (PFKFB3) as a therapeutic strategy against cancer.

Reference:

Mol Cancer Ther. 2013 Aug;12(8):1461-70.

Authors:

Clem BF, O\'Neal J, Tapolsky G, Clem AL, Imbert-Fernandez Y, Kerr DA 2nd, Klarer AC, Redman R, Miller DM, Trent JO, Telang S, Chesney J.

Compounds:

3PO (5284086), PFK15 {Not in Our Database}