Bioactive Small Molecules

Compound I

Compound I (click to show)

Compound I (click to hide)

Title:

Discovery and characterization of inhibitors of human palmitoyl acyltransferases

Reference:

Mol Cancer Ther 2006 Jul;5(7):1647-59.

Authors:

Charles E. Ducker, Lindsay K. Griffel, Ryan A. Smith, Staci N. Keller, Yan Zhuang, Zuping Xia, John D. Diller, and Charles D. Smith

Compounds:

Compound I (5269865), Compound III (5790443), Compound V (5657368)

Compound I (click to show)

Compound I (click to hide)

Title:

2-bromopalmitate and 2-(2-Hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro

Reference:

J. Lipid Res. 2009 Feb;50(2):233-42

Authors:

Jennings BC, Nadolski MJ, Ling Y, Baker MB, Harrison ML, Deschenes RJ, Linder ME.

Compounds:

Compound I (5269865), Compound II (5782183), Compound III (5790443), Compound V (5657368)