Bioactive Small Molecules

5-(diphenylmethyl)-6-hydroxy-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone

Compound 11

Compound 11 (click to show)
Compound 11 (click to hide)
Title:
Thiobarbiturates as Sirtuin Inhibitors: Virtual Screening, Free-Energy Calculations, and Biological Testing
Reference:
ChemMedChem. 2008 Dec;3(12):1965-76.
Authors:
Urszula Uciechowska, Jorg Schemies, Robert C. Neugebauer, Elisabeth-Maria Huda
Compounds:
Compound 7 (6958028), Compound 8 (6988938), Compound 9 (5327543), Compound 10 (5549466), Compound 11 (5240507)