Bioactive Small Molecules

ITSA2, Z2

Z2 (click to show)

Z2 (click to hide)

Title:

Targeting cell division: Small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality

Reference:

PNAS August 10, 2004 vol. 101 no. 32 11821�11826

Authors:

Danielle N. Margalit, Laura Romberg, Rebecca B. Mets , Alan M. Hebert, Timothy J. Mitchison, Marc W. Kirschner, and Debabrata Ray Chaudhuri

Compounds:

Z1 (5175333), Z2 (5233705), Z3 (5175327), Z4 (5141951)

ITSA2 (click to show)

ITSA2 (click to hide)

Title:

Chemical Genetic Modifier Screens: Small Molecule Trichostatin Suppressors as Probes of Intracellular Histone and Tubulin Acetylation

Reference:

Chemistry & Biology, Vol. 10, 397-410, May, 2003

Authors:

Kathryn M. Koeller, Stephen J. Haggarty, Brian D. Perkins, Igor Leykin, Jason C. Wong, Ming-Chih J. Kao, and Stuart L. Schreiber

Compounds:

ITSA1 (5253409), ITSA2 (5233705), ITSA3 (5149715), ITSA4 (5140203), ITSA5 (5248896), nITSA1-A (5273682), nITSA1-B (5286656)