Bioactive Small Molecules

5-(2,3-dihydro-1,4-benzodioxin-2-yl)-4H-1,2,4-triazole-3-thiol

Compound 1

Compound 1 (click to show)
Compound 1 (click to hide)
Title:
Identification of a small molecule that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling.
Reference:
ACS Chem Biol. 2014 Oct 17;9(10):2318-25. Epub 2014 Aug 11.
Authors:
Nakagawa A, Lui FE, Wassaf D, Yefidoff-Freedman R, Casalena D, Palmer MA, Meadows J, Mozzarelli A, Ronda L, Abdulmalik O, Bloch KD, Safo MK, Zapol WM.
Compounds:
Compound 1 (5228930)