Bioactive Small Molecules

CADD522

CADD522 (click to show)

CADD522 (click to hide)

Title:

Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity

Reference:

Oncotarget. 2017 Aug 10;8(41):70916-70940. doi: 10.18632/oncotarget.20200. eCollection 2017 Sep 19.

Authors:

Kim MS, Gernapudi R, Choi EY, Lapidus RG, Passaniti A

Compounds:

CADD522 (5221975)

CADD522 (click to show)

CADD522 (click to hide)

Title:

RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells

Reference:

Oncotarget. 2015 Sep 29;6(29):28132-50. doi: 10.18632/oncotarget.4654.

Authors:

Brusgard JL, Choe M, Chumsri S, Renoud K, MacKerell AD Jr, Sudol M, Passaniti A

Compounds:

CADD522 (5221975)