Bioactive Small Molecules

5210809

5210809 (click to show)

5210809 (click to hide)

Title:

A Brain-Permeable Small Molecule Reduces Neuronal Cholesterol by Inhibiting Activity of Sirtuin 2 Deacetylase

Reference:

ACS Chem Biol. 2011 Jun 17;6(6):540-6. doi: 10.1021/cb100376q. Epub 2011 Mar 9.

Authors:

David M. Taylor, Uma Balabadra, Zhongmin Xiang, Ben Woodman, Sarah Meade, Allison Amore, Michele M. Maxwell, Steven Reeves, Gillian P. Bates, Ruth Luthi-Carter, Philip A. S. Lowden, and Aleksey G. Kazantsev

Compounds:

6648610 (6648610), 6666243 (6666243), 6680310 (6680310), 6670011 (6670011), AK-7 (6672313), AK-1 (6642056), 5210809 (5210809)