Bioactive Small Molecules

C2-8

C2-8 (click to show)

C2-8 (click to hide)

Title:

A potent small molecule inhibits polyglutamine aggregation in Huntington�s disease neurons and suppresses neurodegeneration in vivo

Reference:

PNAS January 18, 2005 vol. 102 no. 3 892-7

Authors:

Xiaoqian Zhang, Donna L. Smith, Anatoli B. Meriin, Sabine Engemann, Deborah E. Russel, Margo Roark, Shetia L. Washington , Michele M. Maxwell, J. Lawrence Marsh , Leslie Michels Thompson, Erich E. Wanker, Anne B. Young, David E. Housman, Gillian P. Bates,

Compounds:

C2 (5253122), C2-8 (5210775)