Bioactive Small Molecules

3-bromo-5-chloro-N-{2-chloro-5-[(4-chlorophenyl)sulfonyl]phenyl}-2-hydroxybenzamide

BH3I-2

BH3I-2 (click to show)
BH3I-2 (click to hide)
Title:
Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL
Reference:
Nat Cell Biol. 2001 Feb;3(2):173-82.
Authors:
Degterev A, Lugovskoy A, Cardone M, Mulley B, Wagner G, Mitchison T, Yuan J.
Compounds:
BH3I-1 (5275805), BH3I-1\' (5282986), BH3I-2 (5175362)