Bioactive Small Molecules

Compound 40

Compound 40 (click to show)

Compound 40 (click to hide)

Title:

Discovery of Indoles as Potent and Selective Inhibitors of the Deacetylase SIRT1

Reference:

J. Med. Chem., 2005 Dec 15;48(25):8045-54.

Authors:

Andrew D. Napper, Jeffrey Hixon, Thomas McDonagh, Kenneth Keavey, Jean-Francois Pons, Jonathan Barker, Wei Tsung Yau, Patricia Amouzegh, Adam Flegg, Estelle Hamelin, Russell J. Thomas, Michael Kates, Stephen Jones, Manuel A. Navia, Jeffrey O. Saunders, Pe

Compounds:

Compound 2 (5651397), Compound 3 (5870454), Compound 36 (5650363), Compound 37 (5665705), Compound 40 (5169181), Compound 41 (5476084)