Bioactive Small Molecules

4-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-N-hydroxybutanamide

5158497, Scriptaid

Scriptaid (click to show)
Scriptaid (click to hide)
Title:
High-Throughput Drug Screening of the DPC4 Tumor-Suppressor Pathway in Human Pancreatic Cancer Cells
Reference:
Annals of Surgery. 2001 May;233(5):696-703
Authors:
Sohn, Taylor A. MD ; Su, Gloria H. PhD ; Ryu, Byungwoo PhD ; Yeo, Charles J. MD ; Kern, Scott E. MD
Compounds:
Scriptaid (5158497)
Scriptaid (click to show)
Scriptaid (click to hide)
Title:
A Novel Histone Deacetylase Inhibitor Identified by High-throughput Transcriptional Screening of a Compound Library
Reference:
Cancer Res. 2000 Jun 15;60(12):3137-42
Authors:
Su, G.H.; Taylor, A.S.; Byungwoo, R.; Kern, S.E.
Compounds:
Scriptaid (5158497)
5158497 (click to show)
5158497 (click to hide)
Title:
Discovery of inhibitors of Schistosoma mansoni HDAC8 by combining homology modeling, virtual screening, and in vitro validation.
Reference:
J Chem Inf Model. 2014 Oct 27;54(10):3005-19. Epub 2014 Oct 2.
Authors:
Kannan S, Melesina J, Hauser AT, Chakrabarti A, Heimburg T, Schmidtkunz K, Walter A, Marek M, Pierce RJ, Romier C, Jung M, Sippl W.
Compounds:
5144030 (5144030), 5158497 (5158497), 5234974 (5234974), 5808200 (5808200), 5809354 (5809354), 6022898 (6022898), 7778127 (7778127), 8879700 (8879700)