Bioactive Small Molecules

AMI-7, Z4

AMI-7 (click to show)

AMI-7 (click to hide)

Title:

Small Molecule Regulators of Protein Arginine Methyltransferases

Reference:

THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 279, No. 23, Issue of June 4, pp. 23892-23899, 2004

Authors:

Donghang Cheng, Neelu Yadav, Randall W. King, Maurice S. Swanson, Edward J. Weinstein, and Mark T. Bedford

Compounds:

AMI-1 (5255879), AMI-2 (5112759), AMI-3 (5255910), AMI-5 (5122150), AMI-6 (5135283), AMI-7 (5141951), AMI-8 (5175464)

Z4 (click to show)

Z4 (click to hide)

Title:

Targeting cell division: Small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality

Reference:

PNAS August 10, 2004 vol. 101 no. 32 11821�11826

Authors:

Danielle N. Margalit, Laura Romberg, Rebecca B. Mets , Alan M. Hebert, Timothy J. Mitchison, Marc W. Kirschner, and Debabrata Ray Chaudhuri

Compounds:

Z1 (5175333), Z2 (5233705), Z3 (5175327), Z4 (5141951)