Bioactive Small Molecules

Eeyarestatin I

Eeyarestatin I (click to show)

Eeyarestatin I (click to hide)

Title:

TFEB regulates lysosomal proteostasis

Reference:

Hum Mol Genet. 2013 May 15;22(10):1994-2009

Authors:

Wensi Song, Fan Wang, Marzia Savini, Ashley Ake, Alberto di Ronza, Marco Sardiello, and Laura Segatori

Compounds:

Eeyarestatin I (5138427)

Eeyarestatin I (click to show)

Eeyarestatin I (click to hide)

Title:

Dissection of the Dislocation Pathway for Type I Membrane Proteins with a New Small Molecule Inhibitor, Eeyarestatin

Reference:

Molecular Biology of the Cell. 2004 Apr;15(4):1635-46

Authors:

Edda Fiebiger, Christian Hirsch, Jatin M. Vyas, Eva Gordon, Hidde L. Ploegh, and Domenico Tortorella

Compounds:

Eeyarestatin I (5138427), Eeyarestatin II (5138490)

Eeyarestatin I (click to show)

Eeyarestatin I (click to hide)

Title:

ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells

Reference:

PNAS, Vol 106, 2200-2205, 2009

Authors:

Qiuyan Wang, Helena Mora-Jensen, Marc A. Weniger, Patricia Perez-Galan, Chris Wolford, Tsonwin Hai, David Ron, Weiping Chen, William Trenkle, Adrian Wiestner, and Yihong Ye

Compounds:

Eeyarestatin I (5138427)

Eeyarestatin I (click to show)

Eeyarestatin I (click to hide)

Title:

Inhibition of p97-dependent Protein Degradation by Eeyarestatin I

Reference:

J. Biol. Chem., 2008 Mar 21;283(12):7445-54.

Authors:

Qiuyan Wang, Lianyun Li, and Yihong Ye

Compounds:

Eeyarestatin I (5138427), MG132 {Not in our database}