Bioactive Small Molecules

Compound 311, NIH

Compound 311 (click to show)

Compound 311 (click to hide)

Title:

Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells

Reference:

Chemistry & Biology, Volume 15, Issue 3, 234-245, 21 March 2008

Authors:

Wan Seok Yang and Brent R. Stockwell

Compounds:

RSL5 (5707885), Compound 311 (5135701)

NIH (click to show)

NIH (click to hide)

Title:

Using High-Throughput Screening Data To Discriminate Compounds with Single-Target Effects from Those with Side Effects

Reference:

J. Chem. Inf. Model., 2006 Jul-Aug;46(4):1549-62

Authors:

Justin Klekota, Erik Brauner, Frederick P. Roth, and Stuart L. Schreiber

Compounds:

NIH (5135701)