Bioactive Small Molecules

Compound 2 (theophylline)

Compound 2 (theophylline) (click to show)

Compound 2 (theophylline) (click to hide)

Title:

Structure-Based Discovery of Novel Chemotypes for Adenosine A2A Receptor Antagonists

Reference:

Journal of Medicinal Chemistry 2010 Feb 25;53(4):1799-809.

Authors:

Vsevolod Katritch, Veli-Pekka Jaakola, J. Robert Lane, Judy Lin, Adriaan P. IJzerman, Mark Yeager, Irina Kufareva, Raymond C. Stevens, Ruben Abagyan

Compounds:

Compound 2 (theophylline) (5126190), Compound 3 (5787474), Compound 17 (5633157), Compound 50 (5630383), Compound 8 (7983589)