Bioactive Small Molecules

5121758

5121758 (click to show)

5121758 (click to hide)

Title:

A Small Nonrule of 3 Compatible Fragment Library Provides High Hit Rate of Endothiapepsin Crystal Structures with Various Fragment Chemotypes

Reference:

J Med Chem. 2011 Nov 24;54(22):7784-96. doi: 10.1021/jm200642w. Epub 2011 Oct 25.

Authors:

Helene Koster, Tobias Craan, Sascha Brass, Christian Herhaus, Matthias Zentgraf, Lars Neumann, Andreas Heine, and Gerhard Klebe

Compounds:

5121758 (5121758), 5790523 (5790523), 7986284 (7986284)