Bioactive Small Molecules

2-(2-imino-4,5,6,7-tetrahydro-1,3-benzothiazol-3(2H)-yl)-1-(4-methylphenyl)ethanone hydrobromide

PFT-alpha, Pifithrin-alpha

PFT-alpha (click to show)
PFT-alpha (click to hide)
Title:
A Chemical Inhibitor of p53 that Protects Mice from the Side Effects of Cancer Therapy
Reference:
Science 1999 Sep 10;285(5434):1733-7.
Authors:
Pavel G. Komarov, , Elena A. Komarova, Roman V. Kondratov, , Konstantin Christov-Tselkov, John S. Coon, Mikhail V. Chernov, Andrei V. Gudkov
Compounds:
PFT-alpha (5120841), Pifithrin-alpha (5120841)