Bioactive Small Molecules

2-{[1-(4-bromophenyl)-2,5-dioxo-3-pyrrolidinyl]thio}-N-2-naphthylacetamide

Lead 4

Lead 4 (click to show)
Lead 4 (click to hide)
Title:
Molecular modeling, quantum polarized ligand docking and structure-based 3D-QSAR analysis of the imidazole series as dual AT(1) and ET(A) receptor antagonists.
Reference:
Acta Pharmacol Sin. 2013 Dec;34(12):1592-606.
Authors:
Singh KD, Muthusamy K.
Compounds:
Lead 1 (7360337), Lead 2 (5924086), Lead 3 (5753900), Lead 4 (5109057), Lead 5 (9152553)