Bioactive Small Molecules

M15

M15 (click to show)

M15 (click to hide)

Title:

Identification of a Class of Small Molecule Inhibitors of the Sirtuin Family of NAD-dependent Deacetylases by Phenotypic Screening

Reference:

J. Biol. Chem. 2001 Oct 19;276(42):38837-43.

Authors:

Grozinger, C. M.; Chao, E.D.; Blackwell, H.E.; Moazed, D.; Schreiber, S.�L.

Compounds:

Sirtinol (5108474), M15 (5104559)

M15 (click to show)

M15 (click to hide)

Title:

Sir2 Regulates Skeletal Muscle Differentiation as a Potential Sensor of the Redox State

Reference:

Molecular Cell, 2003 Jul;12(1):51-62

Authors:

Marcella Fulco, R. Louis Schiltz, Simona Iezzi, M. Todd King, Po Zhao, Yoshihiro Kashiwaya, Eric Hoffman, Richard L. Veech, and Vittorio Sartorelli,

Compounds:

Sirtinol (5108474), M15 (5104559)

M15 (click to show)

M15 (click to hide)

Title:

Genetic and chemical analyses of the action mechanisms of sirtinol in Arabidopsis

Reference:

PNAS 2005, 102 (8), 3129-3134

Authors:

Xinhua Dai, Ken-ichiro Hayashi, Hiroshi Nozaki, Youfa Cheng, and Yunde Zhao

Compounds:

Sirtinol (5108474), M15 (5104559)