Bioactive Small Molecules

Chembridge 5108509

Chembridge 5108509 (click to show)

Chembridge 5108509 (click to hide)

Title:

Novel inhibitors of Mycobacterium tuberculosis dTDP-6-deoxy-L-lyxo-4-hexulose reductase (RmlD) identified by virtual screening.

Reference:

Bioorg Med Chem Lett. 2011 Dec 1;21(23):7064-7. doi: 10.1016/j.bmcl.2011.09.094. Epub 2011 Sep 29.

Authors:

Wang Y, Hess TN, Jones V, Zhou JZ, McNeil MR, Andrew McCammon J.

Compounds:

NSC 9037 (5137132), Chembridge 5108509 (5104346), NSC 5426 {not able to find}, NSC 371300 {not able to find}