Bioactive Small Molecules

N-[(1S)-2,3-dihydro-1H-inden-1-yl]-2-(3-pyridinyl)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-4-amine

640

640 (click to show)
640 (click to hide)
Title:
Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer
Reference:
Sci Signal. 2015 Jan 20;8(360):ra7. doi: 10.1126/scisignal.2005537.
Authors:
Ben-Chetrit N, Chetrit D, Russell R, Korner C, Mancini M, Abdul-Hai A, Itkin T, Carvalho S, Cohen-Dvashi H, Koestler WJ, Shukla K, Lindzen M, Kedmi M, Lauriola M, Shulman Z, Barr H, Seger D, Ferraro DA, Pareja F, Gil-Henn H, Lapidot T, Alon R , Milanezi , Symons M, Ben-Hamo R, Efroni S, Schmitt F, Wiemann S, Caldas C, Ehrlich M, Yarden Y.
Compounds:
278 (16495278), 640 (21391640), 949 (94539949), 280 (11557280)