Introduction

Screening Compounds

Hit2Lead.com®, a division of ChemBridge Corporation, offers unmatched availability of the most comprehensive collection of drug-like chemical entities through its proprietary E-commerce portal. With over 900,000 compounds in stock, Hit2Lead.com® offers convenient access to ChemBridge's screening compounds and building blocks. With the growing number of targets, screens, and screening compounds, hit follow-up is emerging as a critical bottleneck of modern drug discovery. Hit2Lead.com® is geared to address this bottleneck with the best Internet-accessible chemical tools available.

Hit2Lead.com® supports compound queries based on chemical structure and other molecular parameters relevant in discovery research with one of the fastest and most user-friendly search engines.

All compounds meet the high quality standard of 100% NMR identification and have a purity level of at least 90%. Hit2Lead.com® clients have access to SD files of the selected compounds in a secure and encrypted environment.

The security for this site is provided by VeriSign^TM Commerce Site Services and enables visitors to verify our site's authenticity and to communicate with it securely via state-of-the-art SSL encryption, which protects confidential information from interception. The ISIS/Draw^TM (with Chime plugin) software from MDLTM Information Systems provides a safe and easy-to-use structure search tool. The Marvin applet software from ChemAxon can be used as an alternative method for structure drawing.

Compounds with 8-digit IDs belong to our parallel-synthesized in-house screening libraries. These libraries explore pharmacophore space using proprietary building blocks and unpublished novel scaffolds. This leads to libraries that provide our clients with novel, small molecules with improved IP potential.

All such compounds will be supplied as a dry film.